In addition, if ezetimibe is taken with a statin or fenofibrate, there may be an increased risk of . Zetia contains the active drug ezetimibe. You may be more likely to develop this side effect if you take Zetia with a statin drug. The causes of POTS are unknown, but the problem is thought to lie in the communication breakdown between the brain and the cardiovascular system. stuffy nose. We talked to experts about, Healthline has strict sourcing guidelines and relies on peer-reviewed studies, academic research institutions, and medical associations. Learn about side effects, dosage, uses, interactions, and more. If your doctor recommends that you stop taking Zetia, they may suggest another treatment option for your condition. Zetia comes as a tablet that you swallow. Zetia and Lipitor are both brand-name drugs. A malfunctioning ANS is sometimes called 'dysautonomia'. This may increase your risk of side effects. The generic form of Zetia costs about the same as the generic form of Lipitor. However, excessive alcohol use can damage your liver over time. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks and reviews side effects of the medication. Bethenny Frankel is opening up about her health issue, explaining to her Instagram followers about her battle with postural orthostatic tachycardia syndrome (POTS) after receiving comments about . Liver problems. Plant sterols are similar to cholesterol. (A class of drugs is a group of medications that work in a similar way.) They can tell you about other medications that may work well for you. Ezetimibe is used along with a low cholesterol/low fat diet and exercise to help lower cholesterol in the blood. An allergic reaction is possible after using Zetia. Using Zetia with medications in the fibrate drug class raises your risk of gallstones even more. However, you may need to avoid grapefruit if you take Zetia with a statin, another type of cholesterol medication. Talk with your doctor to learn more about which medications are right for you. Zetia reduces the buildup of fats, cholesterol, and other substances on the artery walls (this process is known as atherosclerosis) and if taken long term it may reduce the risk of heart disease. It isnt known how long adults and children experienced diarrhea while taking Zetia in these clinical studies. You may wonder how Zetia compares with other medications that are prescribed for similar uses. Drugs in this class prevent your small intestine from absorbing cholesterol. 2. Lying down on the bed, and raising your legs. Covers lawsuits, malpractice, class actions, fraud, legislation, regulation, enforcement. trouble in swallowing. Is the ketogenic diet right for autoimmune conditions? The Benary's Giants have large, double blossoms, 4 to 6 inches across, available in a rainbow of . joint pain *. Before taking Zetia, talk with your doctor and pharmacist. Do my other medications increase my risk of side effects with Zetia? Despite having lower total cholesterol than white people, African Americans are at greater risk of dying from heart disease. Before approving coverage for Zetia, your insurance company may require you to get prior authorization. POTS is a kind of dysautonomia or autonomic nervous disorder. They can suggest ways to help relieve this side effect. Zetia is sometimes used with medications in the statin drug class. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. Some people witness mild symptoms, some have a big impact on their lives due . Therefore, you shouldnt breastfeed if youre taking Zetia with a statin drug. This drug has not been studied in pregnant females.*. Theyll guide you with suggestions they may have to relieve these side effects. Within 4 to 12 hours of oral administration, a single 10-mg dose of Zetia reaches peak plasma concentrations of 3.4 to 5.5 ng/mL. To help make sure you dont miss a dose, try setting a reminder on your phone. If you have any questions about eating certain foods while taking Zetia, talk with your doctor. Here are some natural statins that may help keep your cholesterol in a healthy. tender, swollen glands in neck. Chylomicrons help your body, low-density lipoproteins (LDL), sometimes referred to as bad cholesterol, high-density lipoproteins (HDL), sometimes referred to as good cholesterol, triglycerides, which are a type of fat that are building blocks of cholesterol, Apo B (high levels of this protein are a sign of high cholesterol), non-HDL cholesterol (calculated by subtracting your HDL cholesterol level from your total cholesterol), were reduced by an average of 13% to 14% in people who used Zetia, ranged from not changing to being reduced by an average of 1% in people who used a placebo, were reduced by an average of 18% in people who used Zetia, increased by an average of 1% in people who used a placebo, decreased by an average of 13% to 14% in people who used Zetia alone, decreased by an average of 15% to 40% in people who used a statin alone, depending on the statin used, decreased by an average of 24% to 46% in people who used Zetia and a statin, depending on the statin used, ranged from decreasing by an average to 1% to increasing by an average of 4% in people who took a placebo, decreased by an average of 19% to 20% in people who used Zetia alone, decreased by an average of 20% to 54% in people who used a statin alone, depending on the statin used, decreased by an average of 34% to 61% in people who used Zetia and a statin, depending on the statin used. Most of Zetias side effects should go away within a few days or weeks. The bottom line: Zetia may cause fewer side effects than statins (though some clinicians might dispute that) but Zetia may cause muscle problems and other adverse reactions. The insurance company will review the prior authorization request and decide if the drug will be covered. Zetia is approved to treat certain forms of high cholesterol in children ages 10 years and older when used with a low-cholesterol diet. Learn about side effects, dosage, and more. Generics tend to cost less than brand-name drugs. 2004-2023 Healthline Media UK Ltd, Brighton, UK, a Red Ventures Company. POTS-related fatigue is physical in nature . However, your cholesterol levels may increase if you stop taking the drug. If taking your dose at bedtime doesnt help, or if dizziness becomes severe, tell your doctor. Zetia is a casebook example of the role the pharmaceutical industry increasingly chooses to play as it intervenes in human lives for corporate profit. Recently, POTS has been diagnosed in some people who have had COVID-19. I take pravastatin 80mg with absolutely no problem. Serious side effects from Zetia arent common, but they can occur. More common side effects in people taking Zetia* include: * In studies, these side effects were reported in people who took Zetia by itself. Its not known if Zetia is safe to take during pregnancy. Zetia shouldnt cause weight gain or weight loss. It also isnt known what percentage of adults and children experienced diarrhea in clinical studies of other conditions treated with Zetia. Both Zetia and Lipitor come as tablets that are swallowed. No, hair loss isnt a known side effect of Zetia. Dizziness is a rare side effect of taking Zetia. High cholesterol may be caused by genetics, smoking, low amounts of physical activity, or eating too many high-cholesterol foods. Its primary metabolic pathway is via hepatic glucuronic conjunction. Statins are drugs used to lower cholesterol. Tell your doctor if youre experiencing bothersome side effects from Zetia. The symptoms develop immediately and include dizziness and an intense headache. If youre taking a statin drug with Zetia, they may recommend that you take a supplement called coenzyme Q10 (CoQ10). Statins lower cholesterol by preventing your liver from making new cholesterol. 22% in people who used Zetia with fenofibrate, 20% in people who used Zetia with fenofibrate, people who used Zetia with atorvastatin or simvastatin had their LDL levels reduced by an average of 21% to 27% (the percentage varied depending on the dosage used), people who used atorvastatin or simvastatin alone had their LDL levels reduced by an average of 7%, people who used Zetia had their sitosterol levels decreased by an average of 21% and their campstrol levels decreased by an average of 24%, people who used a placebo had their sitosterol levels decreased by an average of 4% and their campstrol levels decreased by an average of 3%, bile acid sequestrants, such as cholestyramine (Prevalite, Questran), colesevelam (Welchol), and colestipol (Colestid), statins, such as atorvastatin (Lipitor), rosuvastatin (Crestor), and simvastatin (Zocor), Both Zetia and Lipitor are FDA-approved to treat the following conditions* in adults when used with a. Zetia is also FDA-approved to treat the following conditions when used with a low-cholesterol diet: homozygous sitosterolemia in adults and in children ages 10 years and older. Primary hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. The dosage is the same for all approved uses. diarrhea. If the side effects seem life threatening or if you think youre having a medical emergency, immediately call 911 or your local emergency number. It can develop suddenly or gradually over time. Some people may develop mild or serious side effects during Zetia treatment. Zetia is a brand-name prescription drug. Effects of coenzyme Q10 on statin-induced myopathy: An updated meta-analysis of randomized controlled trials. Here are a few questions to get your discussion started with your doctor: To get information on different conditions and tips for improving your health, subscribe to any of Healthlines newsletters. For this purpose, Zetia is used with a low-cholesterol diet and is taken with atorvastatin or simvastatin in adults and in children ages 10 years and older. Zetias side effects are usually mild, especially if youre taking Zetia alone. fainting (passing out) problems with thinking, memory and concentration - this combination of symptoms is often called 'brain fog'. If youre currently taking cyclosporine, talk with your doctor about whether its safe for you to take Zetia. Memory loss isnt a side effect of Zetia. The manufacturer of Zetia hasnt stated whether the tablets can be crushed, split, or chewed. Is it harmful to take a coenzyme Q10 (CoQ10) supplement along with Zetia to help prevent muscle-related side effects? joint or muscle pain*. This may be caused by genetics, smoking, not getting enough physical activity, or eating too many foods that are high in cholesterol. Call your doctor right away if you have serious side effects. These symptoms could be life threatening and require immediate medical care. Zinnia elegans 'Benary's Giant Golden Yellow'. dark colored urine. These include: Note: For more information about the potential negative effects of Zetia, see the Zetia side effects section above. People with this condition have high levels of LDL (bad) cholesterol. Clinical studies have shown Zetia to be effective for treating homozygous familial hypercholesterolemia when used with atorvastatin or simvastatin. For more information, see the Precautions section below. Zetia is metabolized in the small intestine and liver. Postural orthostatic tachycardia syndrome (POTS) is one of a group of disorders that have orthostatic intolerance (OI) as their primary symptom. However, you shouldnt stop taking Zetia without first talking with your doctor. People with HoFH have high levels of LDL (bad) cholesterol. Ways to reduce the symptoms. Get medical help right away, if you have any of the symptoms listed above. Clinical studies looked at Zetia for the treatment of primary hyperlipidemia in adults and in children ages 10 years and older. These tests will look at your cholesterol levels and also your liver enzyme levels. However, several medicines can be prescribed off-label when needed. If you think youve taken too much of this drug, call your doctor. For this purpose, Zetia is used with a low-cholesterol diet (but with no other drugs) in adults and in children ages 10 years and older. But new medications can help lower cholesterol and improve heart health. Yes, there are a few. Zetia is FDA-approved to lower your total cholesterol level, and triglycerides are one part of your total cholesterol level. For most people, CoQ10 isnt a harmful or dangerous supplement. Note: Zetia isnt approved to lower these types of cholesterol: Cholesterol is measured in several ways. Symptoms: This section is currently in development. If you have questions about using Zetia and cholestyramine together, talk with your doctor. * Zetia is also approved to treat these conditions in children ages 10 years and older. Zetia and Crestor are both brand-name drugs. As with most drugs, some people can have an allergic reaction after taking Zetia. These can be signs of rhabdomyolysis (muscle breakdown), which is a serious medical condition. Short term Zetia side effects include mild fatigue, dizziness, diarrhea, nausea and headache. But reviews and complaints about medications, including Zetia, may not be as reliable as other types of consumer reviews. Zetia may cause serious side effects including: muscle pain, muscle tenderness or weakness, fever, unusual tiredness, and. If you have unused medication that has gone past the expiration date, talk to your pharmacist about whether you might still be able to use it. Use of the terms male and female in this article refers to sex assigned at birth. Zetia may also increase the amount of cholesterol thats stored in your gallbladder. pain in your arms or legs. The primary symptom of OI is lightheadedness or fainting. Ezetimibe can cause the breakdown of muscle tissue . People with this condition have high levels of LDL (bad) cholesterol, high levels of triglycerides, and low levels of HDL (good) cholesterol. Its not known how many adults and children experienced muscle pain in clinical studies of other conditions treated with Zetia and statin drugs. Total cholesterol levels were reduced by an average of: LDL (bad) cholesterol levels were reduced by an average of: Homozygous familial hypercholesterolemia (HoFH) is a rare genetic condition caused by a mutation (change) in the genes that control how cholesterol is cleared from your body. Porphyrias are rare, mainly genetic disorders that affect the body's ability to make hemoglobin. Its not known if its safe to take Zetia while breastfeeding or if the drug passes into breast milk. POTS is an unusual condition in which your heart rate speeds up by 30 or more beats per minute with little or no change in blood pressure. At the end of the study, researchers found that: Mixed hyperlipidemia is a genetic condition caused by a mutation (change) in the genes that control how cholesterol and fats are cleared from your body. Ezetimibe may be used alone or with other drugs (such as "statins" or . Learn how we can help. Instead, it belongs to a class of drugs called cholesterol absorption inhibitors. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. Both drugs are typically taken once each day. See the Mild side effects and Serious side effects sections above for more information. What foods should I avoid while taking Zetia. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Talk with your doctor about birth control options that may be best for you. Talk with your doctor if you have questions about using Zetia to lower your triglyceride levels. Merck, the manufacturer of Zetia, offers a Patient Assistance Program. Zetia is available in a generic form called ezetimibe. Also, Zetia use may cause increased liver enzyme levels, especially if its taken with a statin drug. Brand-name medications usually cost more than generics. Zetia is FDA-approved to treat mixed high cholesterol when used with fenofibrate. This can increase your risk of side effects from either medication. There are no known interactions between Zetia and alcohol. If your cholesterol levels havent started to improve, they may recommend a different treatment for you. Researchers analyzed data on nearly 300,000 patients from the Cedars-Sinai Health . Clinical studies have shown Zetia to be effective for treating homozygous sitosterolemia when used alone. yellowing of your skin or the whites of your eyes, ahajournals.org/doi/10.1161/JAHA.118.009835, organon.com/product/usa/pi_circulars/z/zetia/zetia_pi.pdf, Alternatives to Statins for Lowering Cholesterol. Zetia may cause joint pain. Such an increase in heart rate may mean that your . Pots or postural tachycardia syndrome is, also known as postural orthostatic tachycardia syndrome, is a condition that affects the flow of blood in the heart and brain. For instance, some interactions can interfere with how well a drug works. The following information describes dosages that are commonly used or recommended. Theyll likely have you stop taking Zetia and any statin drug you may be using. Statin drugs arent safe to use during pregnancy. This section doesnt contain all drugs that may interact with Zetia. Note: Some of the drugs listed here are used off-label to treat these specific conditions. This is especially helpful to do when you first start taking new drugs or using a combination of treatments. Twelve weeks of treatment with Zetia and atorvastatin or simvastatin was compared with atorvastatin or simvastatin used alone. Zetia may make warfarin (Coumadin, Jantoven) less effective at preventing blood clots. They can recommend treatments that may help with joint pain, or they may recommend a different treatment option for you. What causes POTS? Learn more about some of the side effects that Zetia may cause. Physicians who treat dysautonomia can be located on our Physician List. Sometimes doctors will recommend taking both a statin medication and Zetia for high cholesterol. POTS is a form of orthostatic intolerance that is associated with the presence of excessive tachycardia and many other symptoms upon standing. High cholesterol occurs when you have more cholesterol in your blood than your body needs. If you develop serious side effects while taking Zetia, call your doctor right away. They can both be taken with or without food. But keep in mind that Zetia is used to reduce cholesterol levels in your blood. Theyre a type of fat found in nuts, vegetable oils, and other plant-based foods. This in turn increases clearance of cholesterol from the blood. The drug information contained herein is subject to change and is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. But its not clear whether this side effect occurred in studies. In clinical studies, Zetia has been found to be effective for treating mixed high cholesterol when used with fenofibrate. (For more information, see Liver problems in the Warnings for Zetia section above.). shaking and sweating. Welchol is a prescription drug used to treat type 2 diabetes and high cholesterol. Taking Zetia with a statin drug may increase your risk of developing some mild or serious side effects. For more information on these side effects, see Side effect details below. If you have questions about weight changes while using Zetia, talk with your doctor. Drugs in this class prevent your small intestine from absorbing cholesterol. And talk with your doctor if you have any questions about eating certain foods with Zetia. . Zetia is also available in a generic form called ezetimibe. When this happens, more cholesterol can then be cleared from your blood by your liver. zetia. The manufacturer of Zetia hasnt given birth control recommendations for males using the drug. Zetia side effects. Clinical studies involved adults and children ages 10 years and older. Zetia generally costs less than Lipitor. For this purpose, Zetia may be used: The only FDA-approved dosage of Zetia is 10 mg once a day. 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With joint pain, muscle tenderness or weakness, fever, unusual,.
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